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Search Results for " c-c motif chemokine 4 "

8

Compounds

51

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T38292 4-(N-Boc-amino)piperidine
4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents. 1.Burrows, J.N., Cumm...
T36982 CXCR3 Antagonist 6c
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC...
T83769 TC 14012 hydrochloride H-Arg-Arg-Nal-Cys-Tyr-Cit-Lys-D-Cit-Pro-Tyr-Arg-Cit-Cys-Arg-NH2
TC 14012, a peptidomimetic compound, acts as both an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4; IC50 = 2.9 nM) and as an agonist for CXCR7, effectively recruiting β-arrestin in HEK293T cells that expres...
T83763 EPI-X4 TFA Endogenous Peptide Inhibitor of CXCR4
EPI-X4, an endogenous peptide fragment of human serum albumin (amino acids 408-423), serves as an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4). It effectively prevents calcium mobilization and receptor in...
T35772 Emestrin
Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacter...
T35463 (±)14(15)-EET (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
T83841 STING Agonist D61 D61,Stimulator of Interferon Genes Agonist D61
STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline phosphatase (SEAP) and IFN-β-inducible reporter genes in cellular as...
T83779 EP4 Antagonist 14 Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. A...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00566 CCL18 Protein, Human, Recombinant (His) Human Yeast
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-04695 CCL4 Protein, Rat, Recombinant (His) Rat Yeast
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T...
TMPY-04050 FAM19A4 Protein, Human, Recombinant (hFc) Human HEK293
FAM19A4 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 40.1 kDa. Accession number: Q96LR4
TMPH-03121 CXCL4 Protein, Pig, Recombinant (His & Myc) Sus scrofa (Pig) E. coli
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophil...
TMPJ-01279 TAFA4 Protein, Human, Recombinant (His) Human E. coli
FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine res...
TMPY-02244 CCL21 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location...
TMPY-00564 MCP-4 Protein, Human, Recombinant (His) Human Yeast
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family ...
TMPJ-00012 CXCL4 Protein, Human, Recombinant (His) Human Human Cells
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with hi...
TMPY-00641 LEC/CCL16 Protein, Human, Recombinant (His) Human E. coli
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is ...
TMPJ-00018 CCL16 Protein, Human, Recombinant Human E. coli
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c...
TMPY-00646 CCL4 Protein, Human, Recombinant (His) Human Yeast
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T...
TMPY-06553 CXCR4 Protein, Human, Recombinant Human HEK293
CXCR4 Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 39.75 kDa. Accession number: P61073-1
TMPH-02567 CCL4 Protein, Mouse, Recombinant (His) Mouse E. coli
Monokine with inflammatory and chemokinetic properties.
TMPJ-01084 CXCL9 Protein, Human, Recombinant (His) Human Human Cells
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPJ-01060 CXCL6 Protein, Human, Recombinant (His) Human Human Cells
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines...
TMPY-00741 CXCL4 Protein, Human, Recombinant Human E. coli
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w...
TMPH-00297 S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO) Bovine E. coli
S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal act...
TMPJ-00864 VEGF165 Protein, Human, Recombinant Human Human Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi) Human HEK293
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated Human,Cynomolgus HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-00749 FGF-2 Protein, Human, Recombinant Human E. coli
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPY-04754 CASK Protein, Human, Recombinant Human Baculovirus-Insect Cells
Peripheral plasma membrane protein CASK, also known as calcium/calmodulin-dependent serine protein kinase, CASK and LIN2, is a nucleus, cytoplasm and cell membrane protein which belongs to theMAGUK family. CASK / LIN2...
TMPY-04471 APEG1 Protein, Human, Recombinant (His) Human E. coli
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled Human HEK293
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPY-01822 PTK9 Protein, Human, Recombinant (His & GST) Human E. coli
Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highl...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi) Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPY-05598 Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-01117 MRAP Protein, Human, Recombinant (hFc) Human HEK293
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,...
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His) Human HEK293
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-00380 ANTXR2 Protein, Human, Recombinant (hFc) Human HEK293
Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneou...
TMPJ-00782 Amyloid Precursor Protein, Human, Recombinant (hFc) Human Human Cells
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His) Human Human Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His) Human Human Cells
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a var...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His) Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPY-00225 CLEC9A Protein, Mouse, Recombinant (hFc) Mouse HEK293
CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 52.1 kDa. Accession number: Q8BRU4-4
TMPY-01823 PTK9 Protein, Human, Recombinant Human E. coli
Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highl...
TMPY-01933 CHI3L2 Protein, Human, Recombinant (His) Human HEK293
Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, follo...
TMPY-00711 CD45 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04565 SRPK3 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 an...
TMPY-04563 CASK Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Peripheral plasma membrane protein CASK, also known as calcium/calmodulin-dependent serine protein kinase, CASK and LIN2, is a nucleus, cytoplasm and cell membrane protein which belongs to theMAGUK family. CASK / LIN2...
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPJ-01333 TEM8/ANTXR1 Protein, Human, Recombinant (His) Human Human Cells
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothel...
TMPJ-01188 CORO6 Protein, Human, Recombinant (His) Human E. coli
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are...
TMPK-00702 ANTXR2 Protein, Human, Recombinant (His) Human HEK293
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultu...
TMPK-01356 SIRP alpha V4 Protein, Human, Recombinant (His & Avi) Human HEK293
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
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CCL18 Protein, Human, Recombinant (His)
TMPY-00566
Species: Human
Expression System: Yeast
CCL4 Protein, Rat, Recombinant (His)
TMPY-04695
Species: Rat
Expression System: Yeast
FAM19A4 Protein, Human, Recombinant (hFc)
TMPY-04050
Species: Human
Expression System: HEK293
CXCL4 Protein, Pig, Recombinant (His & Myc)
TMPH-03121
Species: Sus scrofa (Pig)
Expression System: E. coli
TAFA4 Protein, Human, Recombinant (His)
TMPJ-01279
Species: Human
Expression System: E. coli
CCL21 Protein, Human, Recombinant
TMPY-02244
Species: Human
Expression System: Baculovirus-Insect Cells
MCP-4 Protein, Human, Recombinant (His)
TMPY-00564
Species: Human
Expression System: Yeast
CXCL4 Protein, Human, Recombinant (His)
TMPJ-00012
Species: Human
Expression System: Human Cells
LEC/CCL16 Protein, Human, Recombinant (His)
TMPY-00641
Species: Human
Expression System: E. coli
CCL16 Protein, Human, Recombinant
TMPJ-00018
Species: Human
Expression System: E. coli
CCL4 Protein, Human, Recombinant (His)
TMPY-00646
Species: Human
Expression System: Yeast
CXCR4 Protein, Human, Recombinant
TMPY-06553
Species: Human
Expression System: HEK293
CCL4 Protein, Mouse, Recombinant (His)
TMPH-02567
Species: Mouse
Expression System: E. coli
CXCL9 Protein, Human, Recombinant (His)
TMPJ-01084
Species: Human
Expression System: Human Cells
CXCL6 Protein, Human, Recombinant (His)
TMPJ-01060
Species: Human
Expression System: Human Cells
CXCL4 Protein, Human, Recombinant
TMPY-00741
Species: Human
Expression System: E. coli
S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)
TMPH-00297
Species: Bovine
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
TMPJ-00864
Species: Human
Expression System: Human Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
TMPK-00823
Species: Human
Expression System: HEK293
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293
FGF-2 Protein, Human, Recombinant
TMPY-00749
Species: Human
Expression System: E. coli
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01456
Species: Human
Expression System: HEK293
CASK Protein, Human, Recombinant
TMPY-04754
Species: Human
Expression System: Baculovirus-Insect Cells
APEG1 Protein, Human, Recombinant (His)
TMPY-04471
Species: Human
Expression System: E. coli
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00822
Species: Human
Expression System: HEK293
NT5C3A/NT5C3 Protein, Human, Recombinant
TMPY-02893
Species: Human
Expression System: E. coli
PTK9 Protein, Human, Recombinant (His & GST)
TMPY-01822
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi)
TMPK-00423
Species: Human
Expression System: HEK293
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01451
Species: Human
Expression System: HEK293
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01450
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-05598
Species: Human
Expression System: HEK293
MRAP Protein, Human, Recombinant (hFc)
TMPY-01117
Species: Human
Expression System: HEK293
IL-32 Protein, Human, Recombinant (isoform alpha, His)
TMPY-01033
Species: Human
Expression System: HEK293
ANTXR2 Protein, Human, Recombinant (hFc)
TMPY-00380
Species: Human
Expression System: HEK293
Amyloid Precursor Protein, Human, Recombinant (hFc)
TMPJ-00782
Species: Human
Expression System: Human Cells
CD200R1/CRTR2 Protein, Human, Recombinant (His)
TMPJ-00233
Species: Human
Expression System: Human Cells
CD45R0 Protein, Human, Recombinant (His)
TMPJ-00410
Species: Human
Expression System: Human Cells
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00424
Species: Human
Expression System: HEK293
Caspase-10 Protein, Human, Recombinant (His)
TMPJ-01256
Species: Human
Expression System: E. coli
CLEC9A Protein, Mouse, Recombinant (hFc)
TMPY-00225
Species: Mouse
Expression System: HEK293
PTK9 Protein, Human, Recombinant
TMPY-01823
Species: Human
Expression System: E. coli
CHI3L2 Protein, Human, Recombinant (His)
TMPY-01933
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (hFc)
TMPY-00711
Species: Human
Expression System: HEK293
SRPK3 Protein, Human, Recombinant (His & GST)
TMPY-04565
Species: Human
Expression System: Baculovirus-Insect Cells
CASK Protein, Human, Recombinant (His & GST)
TMPY-04563
Species: Human
Expression System: Baculovirus-Insect Cells
FLT1 Protein, Human, Recombinant (hFc)
TMPY-00119
Species: Human
Expression System: HEK293
TEM8/ANTXR1 Protein, Human, Recombinant (His)
TMPJ-01333
Species: Human
Expression System: Human Cells
CORO6 Protein, Human, Recombinant (His)
TMPJ-01188
Species: Human
Expression System: E. coli
ANTXR2 Protein, Human, Recombinant (His)
TMPK-00702
Species: Human
Expression System: HEK293
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
TMPK-01356
Species: Human
Expression System: HEK293
TargetMol